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Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents

In various mammalian species, including humans, water restriction leads to an acute increase in urinary sodium excretion. This process, known as dehydration natriuresis, helps prevent further accentuation of hypernatremia and the accompanying rise in extracellular tonicity. Serum- and glucocorticoid...

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Detalhes bibliográficos
Main Authors: Chen, Songcang, Grigsby, Christopher L., Law, Christopher S., Ni, Xiping, Nekrep, Nada, Olsen, Keith, Humphreys, Michael H., Gardner, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689130/
https://ncbi.nlm.nih.gov/pubmed/19436108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35314
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