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JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcoma

Although most reports describe the protein kinase integrin-linked kinase (ILK) as a proto-oncogene, occasional studies detail opposing functions in the regulation of normal and transformed cell proliferation, differentiation, and apoptosis. Here, we demonstrated that ILK functions as an oncogene in...

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Main Authors: Durbin, Adam D., Somers, Gino R., Forrester, Michael, Pienkowska, Malgorzata, Hannigan, Gregory E., Malkin, David
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689127/
https://ncbi.nlm.nih.gov/pubmed/19478459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37958
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