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Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells

The branched-chain amino acids (BCAA) are essential amino acids required for protein homeostasis, energy balance, and nutrient signaling. In individuals with deficiencies in BCAA, these amino acids can be preserved through inhibition of the branched-chain-α-ketoacid dehydrogenase (BCKD) complex, the...

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Hlavní autoři: Lu, Gang, Sun, Haipeng, She, Pengxiang, Youn, Ji-Youn, Warburton, Sarah, Ping, Peipei, Vondriska, Thomas M., Cai, Hua, Lynch, Christopher J., Wang, Yibin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689111/
https://ncbi.nlm.nih.gov/pubmed/19411760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38151
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