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Prostaglandin E(2) enhances hematopoietic stem cell homing, survival, and proliferation

Adult hematopoietic stem cells (HSCs) are routinely used to reconstitute hematopoiesis after myeloablation; however, transplantation efficacy and multilineage reconstitution can be limited by inadequate HSC number, or poor homing, engraftment, or self-renewal. Here we report that mouse and human HSC...

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Detalhes bibliográficos
Main Authors: Hoggatt, Jonathan, Singh, Pratibha, Sampath, Janardhan, Pelus, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689046/
https://ncbi.nlm.nih.gov/pubmed/19324903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-201335
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