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The structure of the ankyrin-binding site of β-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties

Spectrin and ankyrin participate in membrane organization, stability, signal transduction, and protein targeting; their interaction is critical for erythrocyte stability. Repeats 14 and 15 of βI-spectrin are crucial for ankyrin recognition, yet the way spectrin binds ankyrin while preserving its rep...

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Detalhes bibliográficos
Main Authors: Stabach, Paul R., Simonović, Ivana, Ranieri, Miranda A., Aboodi, Michael S., Steitz, Thomas A., Simonović, Miljan, Morrow, Jon S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689040/
https://ncbi.nlm.nih.gov/pubmed/19168783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-184291
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