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Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate

DnaK is the canonical Hsp70 molecular chaperone protein from Escherichia coli. Like other Hsp70s, DnaK comprises two main domains: a 44-kDa N-terminal nucleotide-binding domain (NBD) that contains ATPase activity, and a 25-kDa substrate-binding domain (SBD) that harbors the substrate-binding site. H...

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Bibliografiske detaljer
Main Authors: Bertelsen, Eric B., Chang, Lyra, Gestwicki, Jason E., Zuiderweg, Erik R. P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689011/
https://ncbi.nlm.nih.gov/pubmed/19439666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903503106
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