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Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF

A reduction in dopaminergic innervation of the subventricular zone (SVZ) is responsible for the impaired proliferation of its resident precursor cells in this region in Parkinson's disease (PD). Here, we show that this effect involves EGF, but not FGF2. In particular, we demonstrate that dopami...

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Detalhes bibliográficos
Main Authors: O'Keeffe, Gráinne C., Tyers, Pam, Aarsland, Dag, Dalley, Jeffrey W., Barker, Roger A., Caldwell, Maeve A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689002/
https://ncbi.nlm.nih.gov/pubmed/19433789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803955106
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