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Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF

A reduction in dopaminergic innervation of the subventricular zone (SVZ) is responsible for the impaired proliferation of its resident precursor cells in this region in Parkinson's disease (PD). Here, we show that this effect involves EGF, but not FGF2. In particular, we demonstrate that dopami...

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Bibliografske podrobnosti
Main Authors: O'Keeffe, Gráinne C., Tyers, Pam, Aarsland, Dag, Dalley, Jeffrey W., Barker, Roger A., Caldwell, Maeve A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689002/
https://ncbi.nlm.nih.gov/pubmed/19433789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803955106
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