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Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors
G protein-coupled receptors with seven transmembrane α-helices (GPCRs) comprise the largest receptor superfamily and are involved in detecting a wide variety of extracellular stimuli. The availability of high-resolution crystal structures of five prototypical GPCRs, bovine and squid rhodopsin, engin...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688986/ https://ncbi.nlm.nih.gov/pubmed/19433801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903545106 |
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