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Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure

A method is proposed that finds enriched pathways relevant to a studied condition using the measured molecular data and also the structural information of the pathway viewed as a network of nodes and edges. Tests are performed using simulated data and genomic data sets and the method is compared to...

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Detalhes bibliográficos
Main Authors: Thomas, Reuben, Gohlke, Julia M, Stopper, Geffrey F, Parham, Frederick M, Portier, Christopher J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688935/
https://ncbi.nlm.nih.gov/pubmed/19393085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-4-r44
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