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Mechanism of procaspase-8 activation by c-FLIP(L)

Cellular FLICE-inhibitory protein (c-FLIP(L)) is a key regulator of the extrinsic cell death pathway. Although widely regarded as an inhibitor of initiator caspase activation and cell death, c-FLIP(L) is also capable of enhancing procaspase-8 activation through heterodimerization of their respective...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Yu, Jong W., Jeffrey, Philip D., Shi, Yigong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688887/
https://ncbi.nlm.nih.gov/pubmed/19416807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812453106
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