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Interdimer processing mechanism of procaspase-8 activation

The execution of apoptosis depends on the hierarchical activation of caspases. The initiator procaspases become autoproteolytically activated through a less understood process that is triggered by oligomerization. Procaspase-8, an initiator caspase recruited to death receptors, is activated through...

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Detalhes bibliográficos
Main Authors: Chang, David W., Xing, Zheng, Capacio, Vanessa L., Peter, Marcus E., Yang, Xiaolu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC175803/
https://ncbi.nlm.nih.gov/pubmed/12912912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg414
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