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Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells
Thymus-derived Foxp3(+) natural regulatory CD4 T cells (nTregs) prevent autoimmunity through control of pathogenic, autoreactive T cells and other immune effector cells. Using T cell receptor (TCR) transgenic models, diversity within this lineage has been found to be similar to that of conventional...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688872/ https://ncbi.nlm.nih.gov/pubmed/19359477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808493106 |
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