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The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity
Excess copper is poisonous to all forms of life, and copper overloading is responsible for several human pathologic processes. The primary mechanisms of toxicity are unknown. In this study, mutants of Escherichia coli that lack copper homeostatic systems (copA cueO cus) were used to identify intrace...
Gorde:
Egile Nagusiak: | , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
National Academy of Sciences
2009
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688863/ https://ncbi.nlm.nih.gov/pubmed/19416816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812808106 |
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