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The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity

Excess copper is poisonous to all forms of life, and copper overloading is responsible for several human pathologic processes. The primary mechanisms of toxicity are unknown. In this study, mutants of Escherichia coli that lack copper homeostatic systems (copA cueO cus) were used to identify intrace...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Macomber, Lee, Imlay, James A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688863/
https://ncbi.nlm.nih.gov/pubmed/19416816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812808106
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