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Radial chromatin positioning is shaped by local gene density, not by gene expression
G- and R-bands of metaphase chromosomes are characterized by profound differences in gene density, CG content, replication timing, and chromatin compaction. The preferential localization of gene-dense, transcriptionally active, and early replicating chromatin in the nuclear interior and of gene-poor...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688818/ https://ncbi.nlm.nih.gov/pubmed/17333233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-007-0098-4 |
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