Radial chromatin positioning is shaped by local gene density, not by gene expression

G- and R-bands of metaphase chromosomes are characterized by profound differences in gene density, CG content, replication timing, and chromatin compaction. The preferential localization of gene-dense, transcriptionally active, and early replicating chromatin in the nuclear interior and of gene-poor...

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Hlavní autoři: Küpper, Katrin, Kölbl, Alexandra, Biener, Dorothee, Dittrich, Sandra, von Hase, Johann, Thormeyer, Tobias, Fiegler, Heike, Carter, Nigel P., Speicher, Michael R., Cremer, Thomas, Cremer, Marion
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688818/
https://ncbi.nlm.nih.gov/pubmed/17333233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-007-0098-4
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