SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart

SRp38 is an atypical SR protein splicing regulator. To define the functions of SRp38 in vivo, we generated SRp38-null mice. The majority of homozygous mutants survived only until E15.5 and displayed multiple cardiac defects. Evaluation of gene expression profiles in the SRp38(−/−) embryonic heart re...

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Bibliografski detalji
Glavni autori: Feng, Ying, Valley, Matthew T., Lazar, Josef, Yang, Allison L., Bronson, Roderick T., Firestein, Stuart, Coetzee, William A., Manley, James L.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688787/
https://ncbi.nlm.nih.gov/pubmed/19386262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.02.009
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