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Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator
SRp38 is an atypical SR protein that functions as a general splicing repressor when dephosphorylated. We now show that phosphorylated SRp38 functions as a sequence-specific splicing activator. Unlike characterized splicing activators, SRp38 functions in the absence of other SR proteins but requires...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668916/ https://ncbi.nlm.nih.gov/pubmed/18794844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1485 |
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