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High Specificity of Quantitative Methylation-Specific PCR Analysis for MGMT Promoter Hypermethylation Detection in Gliomas

Normal brain tissue from 28 individuals and 50 glioma samples were analyzed by real-time Quantitative Methylation-Specific PCR (QMSP). Data from this analysis were compared with results obtained on the same samples by MSP. QMSP analysis demonstrated a statistically significant difference in both met...

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Détails bibliographiques
Auteurs principaux: Parrella, Paola, la Torre, Antonella, Copetti, Massimiliano, Valori, Vanna M., Barbano, Raffaela, Notarangelo, Angelo, Bisceglia, Michele, Gallo, Antonietta Pia, Balsamo, Teresa, Poeta, Maria Luana, Carella, Massimo, Catapano, Domenico, Parisi, Salvatore, Dallapiccola, Bruno, Maiello, Evaristo, D'Angelo, Vincenzo, Fazio, Vito Michele
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688744/
https://ncbi.nlm.nih.gov/pubmed/19503806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/531692
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