Blockade of NF-κB using IκBκ dominant negative mice ameliorates cardiac hypertrophy in myotrophin overexpressed transgenic mice

NF-κB is a ubiquitous transcription factor that regulates various kinds of genes including inflammatory molecules, macrophage infiltration factors, cell adhesion molecules, etc., in various disease processes including cardiac hypertrophy and heart failure (HF). Previously, we have demonstrated that...

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Bibliographic Details
Main Authors: Young, David, Popovic, Zoran B., Jones, W. Keith, Gupta, Sudhiranjan
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688722/
https://ncbi.nlm.nih.gov/pubmed/18620706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.076
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