Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity

It is widely accepted that reactive oxygen species (ROS) promote tumorigenesis. However, the exact mechanisms are still unclear. As mice lacking the peroxidase peroxiredoxin1 (Prdx1) produce more cellular ROS and die prematurely of cancer, they offer an ideal model system to study ROS-induced tumori...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cao, Juxiang, Schulte, Jennifer, Knight, Alexander, Leslie, Nicholas R, Zagozdzon, Agnieszka, Bronson, Roderick, Manevich, Yefim, Beeson, Craig, Neumann, Carola A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688529/
https://ncbi.nlm.nih.gov/pubmed/19369943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.101
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados