Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae

BACKGROUND: Xylose reductase (XR) and xylitol dehydrogenase (XDH) from Pichia stipitis are the two enzymes most commonly used in recombinant Saccharomyces cerevisiae strains engineered for xylose utilization. The availability of NAD(+ )for XDH is limited during anaerobic xylose fermentation because...

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Autori principali: Bengtsson, Oskar, Hahn-Hägerdal, Bärbel, Gorwa-Grauslund, Marie F
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688486/
https://ncbi.nlm.nih.gov/pubmed/19416504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-6834-2-9
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