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Enhancing the Antitumor Activity of Adriamycin and Ionizing Radiation
Overexpression of MnSOD when combined with certain chemicals that inhibit peroxide removal increases cancer cell cytotoxicity. Elevating MnSOD levels in cells enhances the conversion of superoxide (O(2)(•−)) to hydrogen peroxide (H(2)O(2)), combined with inhibiting the removal of H(2)O(2), further i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688464/ https://ncbi.nlm.nih.gov/pubmed/19401447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0396 |
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