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Twist-1 is a PPAR δ-inducible, negative feedback regulator of PGC-1 α in brown fat metabolism

Brown fat is specialized in energy expenditure, a process that is principally controlled by the transcriptional co-activator PGC-1α. Here we describe a molecular network important for PGC-1α function and brown fat metabolism. We find that twist-1 is selectively expressed in adipose tissue, interacts...

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Detalhes bibliográficos
Main Authors: Pan, Dongning, Fujimoto, Masaki, Lopes, Andrea, Wang, Yong-Xu
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688451/
https://ncbi.nlm.nih.gov/pubmed/19345188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.01.051
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