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Crystallization of the flexible nuclear import receptor importin-β in the unliganded state

The transport of macromolecules across the nuclear envelope is an essential eukaryotic process that enables proteins such as transcription factors, poly­merases and histones to gain access to the genetic material contained within the nucleus. Importin-β plays a central role in the nucleocytoplasmic...

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Main Authors: Roman, Noelia, Kirkby, Brenda, Marfori, Mary, Kobe, Bostjan, Forwood, Jade K.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688427/
https://ncbi.nlm.nih.gov/pubmed/19478448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109016820
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