Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration

INTRODUCTION: Rheumatoid arthritis (RA) leads to progressive destruction of articular cartilage. This study aimed to disclose major mechanisms of antirheumatic drug action on human chondrocytes and to reveal marker and pharmacological target genes that are involved in cartilage dysfunction and regen...

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Dades bibliogràfiques
Autors principals: Andreas, Kristin, Häupl, Thomas, Lübke, Carsten, Ringe, Jochen, Morawietz, Lars, Wachtel, Anja, Sittinger, Michael, Kaps, Christian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688247/
https://ncbi.nlm.nih.gov/pubmed/19192274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2605
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