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Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration

INTRODUCTION: Rheumatoid arthritis (RA) leads to progressive destruction of articular cartilage. This study aimed to disclose major mechanisms of antirheumatic drug action on human chondrocytes and to reveal marker and pharmacological target genes that are involved in cartilage dysfunction and regen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Andreas, Kristin, Häupl, Thomas, Lübke, Carsten, Ringe, Jochen, Morawietz, Lars, Wachtel, Anja, Sittinger, Michael, Kaps, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688247/
https://ncbi.nlm.nih.gov/pubmed/19192274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2605
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