Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis

INTRODUCTION: Septic encephalopathy secondary to a breakdown of the blood-brain barrier (BBB) is a known complication of sepsis. However, its pathophysiology remains unclear. The present study investigated the effect of complement C5a blockade in preventing BBB damage and pituitary dysfunction durin...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Flierl, Michael A, Stahel, Philip F, Rittirsch, Daniel, Huber-Lang, Markus, Niederbichler, Andreas D, Hoesel, L Marco, Touban, Basel M, Morgan, Steven J, Smith, Wade R, Ward, Peter A, Ipaktchi, Kyros
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688129/
https://ncbi.nlm.nih.gov/pubmed/19196477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7710
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi