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DISCOVER: a feature-based discriminative method for motif search in complex genomes

Motivation: Identifying transcription factor binding sites (TFBSs) encoding complex regulatory signals in metazoan genomes remains a challenging problem in computational genomics. Due to degeneracy of nucleotide content among binding site instances or motifs, and intricate ‘grammatical organization’...

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Bibliografiska uppgifter
Huvudupphovsmän: Fu, Wenjie, Ray, Pradipta, Xing, Eric P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687984/
https://ncbi.nlm.nih.gov/pubmed/19478006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp230
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