Genome-wide detection and characterization of positive selection in human populations

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2)1. We used ‘long-range haplotype’ methods, whic...

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Detalhes bibliográficos
Main Authors: Sabeti, Pardis C., Varilly, Patrick, Fry, Ben, Lohmueller, Jason, Hostetter, Elizabeth, Cotsapas, Chris, Xie, Xiaohui, Byrne, Elizabeth H., McCarroll, Steven A., Gaudet, Rachelle, Schaffner, Stephen F., Lander, Eric S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687721/
https://ncbi.nlm.nih.gov/pubmed/17943131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06250
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