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Exposure and Toxicity of Green Tea Polyphenols in Fasted and Non-Fasted Dogs

Standardized green tea extract was evaluated for exposure and toxicity in Beagle dogs following oral dosing by capsules. The main component (–)-epigallocatechin gallate (EGCG) accounted for 56-72% of the material. A 9-month chronic study (0, 200, 500, and 1000 mg/kg/day) was done in fasted dogs to t...

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Autors principals: Kapetanovic, I.M., Crowell, J.A., Krishnaraj, R., Zakharov, A., Lindeblad, M., Lyubimov, A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687403/
https://ncbi.nlm.nih.gov/pubmed/19464566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2009.03.007
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