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Widespread Phosphorylation of Histone H2AX by Species C Adenovirus Infection Requires Viral DNA Replication

Adenovirus infection activates cellular DNA damage response and repair pathways. Viral proteins that are synthesized before viral DNA replication prevent recognition of viral genomes as a substrate for DNA repair by targeting members of the sensor complex composed of Mre11/Rad50/NBS1 for degradation...

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Detalhes bibliográficos
Main Authors: Nichols, Gena J., Schaack, Jerome, Ornelles, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687384/
https://ncbi.nlm.nih.gov/pubmed/19321613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00091-09
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