Genetic Analysis of Colistin Resistance in Salmonella enterica Serovar Typhimurium

Colistin is a cyclic cationic peptide that kills gram-negative bacteria by interacting with and disrupting the outer membrane. We isolated 44 independent mutants in Salmonella enterica serovar Typhimurium with reduced susceptibility to colistin and identified 27 different missense mutations located...

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Bibliographic Details
Main Authors: Sun, Song, Negrea, Aurel, Rhen, Mikael, Andersson, Dan I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687247/
https://ncbi.nlm.nih.gov/pubmed/19332669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01016-08
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