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Pharmacokinetics of Nikkomycin Z after Single Rising Oral Doses

Nikkomycin Z is an antifungal drug that inhibits chitin synthase. This agent is under development as an orphan product for treatment of coccidioidomycosis. Safety and pharmacokinetics of nikkomycin Z were evaluated in healthy male subjects following single, rising oral doses ranging from 250 mg to 2...

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Detalhes bibliográficos
Main Authors: Nix, David E., Swezey, Robert R., Hector, Richard, Galgiani, John N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687243/
https://ncbi.nlm.nih.gov/pubmed/19349517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01609-08
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