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Pharmacokinetics of EDP-420 after Ascending Single Oral Doses in Healthy Adult Volunteers

EDP-420 (EP-013420, S-013420) is a first-in-class bicyclolide (bridged bicyclic macrolide) currently in clinical development for the treatment of respiratory tract infections. It has good preclinical pharmacokinetic properties across multiple species and potent in vitro and in vivo activity against...

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Detalhes bibliográficos
Main Authors: Jiang, Li-Juan, Wang, Michelle, Or, Yat Sun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681569/
https://ncbi.nlm.nih.gov/pubmed/19223626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01270-08
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