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Pharmacokinetics of EDP-420 after Ascending Single Oral Doses in Healthy Adult Volunteers
EDP-420 (EP-013420, S-013420) is a first-in-class bicyclolide (bridged bicyclic macrolide) currently in clinical development for the treatment of respiratory tract infections. It has good preclinical pharmacokinetic properties across multiple species and potent in vitro and in vivo activity against...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology (ASM)
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681569/ https://ncbi.nlm.nih.gov/pubmed/19223626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01270-08 |
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