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Prediction of the Pharmacodynamically Linked Variable of Oseltamivir Carboxylate for Influenza A Virus Using an In Vitro Hollow-Fiber Infection Model System

MDCK cells transfected with the human β-galactoside α-2,6-sialyltransferase 1 gene (AX-4 cells) were used to determine the drug susceptibility and pharmacodynamically linked variable of oseltamivir for influenza virus. For dose-ranging studies, five hollow-fiber units were charged with 10(2) A/Sydne...

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Bibliografiska uppgifter
Huvudupphovsmän: McSharry, James J., Weng, Qingmei, Brown, Ashley, Kulawy, Robert, Drusano, George L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687202/
https://ncbi.nlm.nih.gov/pubmed/19364864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00167-09
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