Pharmacodynamics of Abacavir in an In Vitro Hollow-Fiber Model System

Abacavir is a potent new carbocyclic nucleoside analogue. We employed our hollow-fiber pharmacodynamic modeling system to examine the antiretroviral effects of different abacavir exposures, as well as the impact of the schedule of drug administration on efficacy. Dose ranging of abacavir revealed th...

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Bibliografiska uppgifter
Huvudupphovsmän: Drusano, G. L., Bilello, P. A., Symonds, W. T., Stein, D. S., McDowell, J., Bye, A., Bilello, J. A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC127059/
https://ncbi.nlm.nih.gov/pubmed/11796359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.2.464-470.2002
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