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Concentrations of Voriconazole in Healthy and Inflamed Lung in Rats

By utilizing the microdialysis technique, we investigated the pharmacokinetic profile of voriconazole in the interstitium of the lungs and skeletal muscle tissue of rats after a single intravenous dose under healthy and inflammatory conditions. As expected, voriconazole penetrated excellently into t...

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Detalhes bibliográficos
Main Authors: Joukhadar, Christian, Thallinger, Christiane, Pöppl, Wolfgang, Kovar, Florian, Konz, Karl H., Joukhadar, Samir M., Traunmüller, Friederike
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687183/
https://ncbi.nlm.nih.gov/pubmed/19332681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00885-08
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