Identification of a Polymyxin Synthetase Gene Cluster of Paenibacillus polymyxa and Heterologous Expression of the Gene in Bacillus subtilis

Polymyxin, a long-known peptide antibiotic, has recently been reintroduced in clinical practice because it is sometimes the only available antibiotic for the treatment of multidrug-resistant gram-negative pathogenic bacteria. Lack of information on the biosynthetic genes of polymyxin, however, has l...

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Hlavní autoři: Choi, Soo-Keun, Park, Soo-Young, Kim, Rumi, Kim, Seong-Bin, Lee, Choong-Hwan, Kim, Jihyun F., Park, Seung-Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Genetics and Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687177/
https://ncbi.nlm.nih.gov/pubmed/19304848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01728-08
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