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Efficient Production of Polymyxin in the Surrogate Host Bacillus subtilis by Introducing a Foreign ectB Gene and Disrupting the abrB Gene
In our previous study, Bacillus subtilis strain BSK3S, containing a polymyxin biosynthetic gene cluster from Paenibacillus polymyxa, could produce polymyxin only in the presence of exogenously added l-2,4-diaminobutyric acid (Dab). The dependence of polymyxin production on exogenous Dab was removed...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370512/ https://ncbi.nlm.nih.gov/pubmed/22467510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.07912-11 |
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