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Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7
The cytolytic P2X7 purinoceptor is widely expressed on leukocytes and has sparked interest because of its key role in the activation of the inflammasome, the release of the pro-inflammatory cytokine IL-1β and cell death. We report here the functional characterisation of a R276A gain-of-function muta...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Netherlands
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686824/ https://ncbi.nlm.nih.gov/pubmed/19234763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-009-9134-6 |
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