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Mammalian nitrilase 1 homologue Nit1 is a negative regulator in T cells
The mammalian Nit1 protein is homologous to plant and bacterial nitrilases. In flies and worms, Nit1 is fused to the 5′ end of Fhit, suggesting that Nit1 may functionally interact with the Fhit pathway. Fhit has been shown to play a role of a tumor suppressor. Somatic loss of Fhit in human tissues i...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686614/ https://ncbi.nlm.nih.gov/pubmed/19395373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxp038 |
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