Convergence of IL-1β and VDR Activation Pathways in Human TLR2/1-Induced Antimicrobial Responses

Antimicrobial effector mechanisms are central to the function of the innate immune response in host defense against microbial pathogens. In humans, activation of Toll-like receptor 2/1 (TLR2/1) on monocytes induces a vitamin D dependent antimicrobial activity against intracellular mycobacteria. Here...

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Detalhes bibliográficos
Main Authors: Liu, Philip T., Schenk, Mirjam, Walker, Valencia P., Dempsey, Paul W., Kanchanapoomi, Melissa, Wheelwright, Matthew, Vazirnia, Aria, Zhang, Xiaoran, Steinmeyer, Andreas, Zügel, Ulrich, Hollis, Bruce W., Cheng, Genhong, Modlin, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686169/
https://ncbi.nlm.nih.gov/pubmed/19503839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005810
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