Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D–dependent mechanism

An essential element of the innate immune response to injury is the capacity to recognize microbial invasion and stimulate production of antimicrobial peptides. We investigated how this process is controlled in the epidermis. Keratinocytes surrounding a wound increased expression of the genes coding...

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Hlavní autoři: Schauber, Jürgen, Dorschner, Robert A., Coda, Alvin B., Büchau, Amanda S., Liu, Philip T., Kiken, David, Helfrich, Yolanda R., Kang, Sewon, Elalieh, Hashem Z., Steinmeyer, Andreas, Zügel, Ulrich, Bikle, Daniel D., Modlin, Robert L., Gallo, Richard L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1784003/
https://ncbi.nlm.nih.gov/pubmed/17290304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30142
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