Sulindac Enhances the Killing of Cancer Cells Exposed to Oxidative Stress

BACKGROUND: Sulindac is an FDA-approved non-steroidal anti-inflammatory drug (NSAID) that affects prostaglandin production by inhibiting cyclooxygenases (COX) 1 and 2. Sulindac has also been of interest for more than decade as a chemopreventive for adenomatous colorectal polyps and colon cancer. PRI...

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Главные авторы: Marchetti, Maria, Resnick, Lionel, Gamliel, Edna, Kesaraju, Shailaja, Weissbach, Herbert, Binninger, David
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686156/
https://ncbi.nlm.nih.gov/pubmed/19503837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005804
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