Sulindac Enhances the Killing of Cancer Cells Exposed to Oxidative Stress

BACKGROUND: Sulindac is an FDA-approved non-steroidal anti-inflammatory drug (NSAID) that affects prostaglandin production by inhibiting cyclooxygenases (COX) 1 and 2. Sulindac has also been of interest for more than decade as a chemopreventive for adenomatous colorectal polyps and colon cancer. PRI...

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Bibliografiske detaljer
Main Authors: Marchetti, Maria, Resnick, Lionel, Gamliel, Edna, Kesaraju, Shailaja, Weissbach, Herbert, Binninger, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686156/
https://ncbi.nlm.nih.gov/pubmed/19503837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005804
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