CNTO 530 functions as a potent EPO mimetic via unique sustained effects on bone marrow proerythroblast pools

Anemia as associated with numerous clinical conditions can be debilitating, but frequently can be treated via administration of epoetin-alfa, darbepoietin-alfa, or methoxy-PEG epoetin-beta. Despite the complexity of EPO-EPO receptor interactions, the development of interesting EPO mimetic peptides (...

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Hlavní autoři: Sathyanarayana, Pradeep, Houde, Estelle, Marshall, Deborah, Volk, Amy, Makropoulos, Dorie, Emerson, Christine, Pradeep, Anamika, Bugelski, Peter J., Wojchowski, Don M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Red Cells, Iron, and Erythropoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686145/
https://ncbi.nlm.nih.gov/pubmed/19264917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-172320
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