The Wnt Co-Receptor Lrp6 Is Required for Normal Mouse Mammary Gland Development

Canonical Wnt signals are transduced through a Frizzled receptor and either the LRP5 or LRP6 co-receptor; such signals play central roles during development and in disease. We have previously shown that Lrp5 is required for ductal stem cell activity and that loss of Lrp5 delays normal mammary develo...

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Autori principali: Lindvall, Charlotta, Zylstra, Cassandra R., Evans, Nicole, West, Richard A., Dykema, Karl, Furge, Kyle A., Williams, Bart O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686096/
https://ncbi.nlm.nih.gov/pubmed/19503830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005813
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