Structural insights into the inhibited states of the Mer receptor tyrosine kinase

The mammalian ortholog of the retroviral oncogene v-Eyk, and a receptor tyrosine kinase upstream of antiapoptotic and transforming signals, Mer (MerTK) is a mediator of the phagocytic process, being involved in retinal and immune cell clearance and platelet aggregation. Mer knockout mice are viable...

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Hauptverfasser: Huang, Xudong, Finerty, Patrick, Walker, John R., Butler-Cole, Christine, Vedadi, Masoud, Schapira, Matthieu, Parker, Sirlester A., Turk, Benjamin E., Thompson, Debra A., Dhe-Paganon, Sirano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686088/
https://ncbi.nlm.nih.gov/pubmed/19028587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2008.10.003
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