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Effects of Schisandra sphenanthera extract on the pharmacokinetics of midazolam in healthy volunteers
AIMS: To assess the effect of Schisandra sphenanthera extract (SchE) on the pharmacokinetics of midazolam, a probe drug of CYP3A, and its metabolite 1′-hydroxy midazolam in healthy volunteers. METHODS: Twelve healthy male volunteers were orally treated with SchE, three capsules twice daily for 7 day...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686071/ https://ncbi.nlm.nih.gov/pubmed/19552749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03383.x |
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