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Methylation-sensitive Regulation of TMS1/ASC by the Ets Factor, GA-binding Protein-α

Epigenetic silencing involving the aberrant DNA methylation of promoter-associated CpG islands is one mechanism leading to the inactivation of tumor suppressor genes in human cancers. However, the molecular mechanisms underlying this event remains poorly understood. TMS1/ASC is a novel proapoptotic...

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Detalhes bibliográficos
Main Authors: Lucas, Mary E., Crider, Krista S., Powell, Doris R., Kapoor-Vazirani, Priya, Vertino, Paula M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685652/
https://ncbi.nlm.nih.gov/pubmed/19324871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M901104200
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